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PF 431396
CAS No. 717906-29-1
PF 431396( PF-431396 | PF 431396 | PF431396 )
Catalog No. M19031 CAS No. 717906-29-1
PF-431396 is a dual PYK2/FAK inhibitor (IC50: 11/2 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 45 | In Stock |
|
| 10MG | 67 | In Stock |
|
| 25MG | 133 | In Stock |
|
| 50MG | 235 | In Stock |
|
| 100MG | 402 | In Stock |
|
| 200MG | 593 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePF 431396
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NoteResearch use only, not for human use.
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Brief DescriptionPF-431396 is a dual PYK2/FAK inhibitor (IC50: 11/2 nM).
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DescriptionPF-431396 is a potent and selective focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2) inhibitor (IC50 values are 2 and 11 nM respectively).
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In Vitro——
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In Vivo——
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SynonymsPF-431396 | PF 431396 | PF431396
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PathwayOthers
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TargetOther Targets
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RecptorFAK| PYK2
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Research AreaEndocrinology
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Indication——
Chemical Information
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CAS Number717906-29-1
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Formula Weight506.5
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Molecular FormulaC22H21F3N6O3S
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Purity>98% (HPLC)
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Solubility——
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SMILESn1c(nc(c(c1)C(F)(F)F)NCc1c(cccc1)N(C)S(=O)(=O)C)Nc1ccc2c(c1)CC(=O)N2
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Chemical NameN-Methyl-N-[2-[[[2-[(2,3-dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]phenyl]methanesulfonamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Han S, et al. J Biol Chem. 2009, 284(19), 13193-13201.
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